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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XPNPEP3X-prolyl aminopeptidase 3. (332 aa)    
Predicted Functional Partners:
PMPCA
Peptidase, mitochondrial processing alpha subunit; Belongs to the peptidase M16 family.
   
 
 0.734
MIPEP
Mitochondrial intermediate peptidase.
   
 
 0.733
C8A
Complement C8 alpha chain.
   
  
 0.693
ATP23
Mitochondrial inner membrane protease ATP23; Belongs to the peptidase M76 family.
      
 0.655
OMA1
OMA1 zinc metallopeptidase.
  
  
 0.585
DNPEP
Aspartyl aminopeptidase; Belongs to the peptidase M18 family.
   
 
 0.576
EDNRB
Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.
      
 0.575
DSC2
Desmocollin 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
      
 0.555
ANKS3
Ankyrin repeat and sterile alpha motif domain containing 3.
    
 0.551
C8B
Complement C8 beta chain.
   
  
 0.546
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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