G3SZS8_LOXAF protein (Loxodonta africana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

G3SZS8_LOXAF

Uncharacterized protein. (135 aa)

Predicted Functional Partners:

RYR1

0.981

RYR2

0.949

CASQ2

0.931

ASPH

0.918

RYR3

0.916

CASQ1

0.899

HRC

0.881

EMC10

0.705

EMC2

0.665

CMYA5

0.642

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASPH	CASQ1	ENSLAFP00000011119	ENSLAFP00000005424	Aspartate beta-hydroxylase.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.882
ASPH	CASQ2	ENSLAFP00000011119	ENSLAFP00000002721	Aspartate beta-hydroxylase.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.882
ASPH	G3SZS8_LOXAF	ENSLAFP00000011119	ENSLAFP00000006155	Aspartate beta-hydroxylase.	Uncharacterized protein.	0.918
ASPH	RYR1	ENSLAFP00000011119	ENSLAFP00000026759	Aspartate beta-hydroxylase.	Ryanodine receptor 1.	0.946
ASPH	RYR2	ENSLAFP00000011119	ENSLAFP00000005517	Aspartate beta-hydroxylase.	Ryanodine receptor 2.	0.966
ASPH	RYR3	ENSLAFP00000011119	ENSLAFP00000028747	Aspartate beta-hydroxylase.	Ryanodine receptor 3.	0.912
CASQ1	ASPH	ENSLAFP00000005424	ENSLAFP00000011119	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Aspartate beta-hydroxylase.	0.882
CASQ1	CASQ2	ENSLAFP00000005424	ENSLAFP00000002721	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.762
CASQ1	G3SZS8_LOXAF	ENSLAFP00000005424	ENSLAFP00000006155	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Uncharacterized protein.	0.899
CASQ1	RYR1	ENSLAFP00000005424	ENSLAFP00000026759	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 1.	0.912
CASQ1	RYR2	ENSLAFP00000005424	ENSLAFP00000005517	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 2.	0.899
CASQ1	RYR3	ENSLAFP00000005424	ENSLAFP00000028747	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 3.	0.849
CASQ2	ASPH	ENSLAFP00000002721	ENSLAFP00000011119	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Aspartate beta-hydroxylase.	0.882
CASQ2	CASQ1	ENSLAFP00000002721	ENSLAFP00000005424	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.762
CASQ2	G3SZS8_LOXAF	ENSLAFP00000002721	ENSLAFP00000006155	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Uncharacterized protein.	0.931
CASQ2	RYR1	ENSLAFP00000002721	ENSLAFP00000026759	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 1.	0.913
CASQ2	RYR2	ENSLAFP00000002721	ENSLAFP00000005517	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 2.	0.899
CASQ2	RYR3	ENSLAFP00000002721	ENSLAFP00000028747	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 3.	0.849
CMYA5	G3SZS8_LOXAF	ENSLAFP00000011506	ENSLAFP00000006155	Uncharacterized protein.	Uncharacterized protein.	0.642
EMC10	EMC2	ENSLAFP00000024508	ENSLAFP00000021210	ER membrane protein complex subunit 10.	ER membrane protein complex subunit 2.	0.980

page 1 of 3

Server load: low (18%) [HD]

Permalink

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About