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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRRX1Paired related homeobox 1. (245 aa)    
Predicted Functional Partners:
ZNF366
Zinc finger protein 366.
   
 
 0.637
GLIS1
GLIS family zinc finger 1.
   
 
 0.625
HHEX
Hematopoietically expressed homeobox.
      
 0.577
FKBP10
Peptidylprolyl isomerase.
   
  
 0.539
SOX8
SRY-box transcription factor 8.
    
 
 0.530
UBXN11
UBX domain protein 11.
      
 0.514
GPSM1
G protein signaling modulator 1.
      
 0.513
MRGPRF
MAS related GPR family member F; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.492
C9orf131
Chromosome 9 open reading frame 131.
    
 
 0.484
COL1A1
Collagen type I alpha 1 chain.
   
 
 0.484
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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