STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (317 aa)    
Predicted Functional Partners:
DDX6
DEAD-box helicase 6; Belongs to the DEAD box helicase family.
   
 
 0.931
EDC3
Enhancer of mRNA decapping 3.
   
   0.927
DCP1A
Decapping mRNA 1A.
    
   0.927
DCP1B
Decapping mRNA 1B.
    
   0.927
PIM2
Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
     
  0.870
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
  0.813
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
  0.813
EGFR
Receptor protein-tyrosine kinase.
    
   0.771
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
   
  
 0.676
MYC
Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
    
 0.628
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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