NLRC3 protein (Loxodonta africana) - STRING interaction network

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NLRC3

NLR family CARD domain containing 3. (1037 aa)

Predicted Functional Partners:

PYCARD

0.703

AK9

0.682

G3TCK5_LOXAF

0.682

MAVS

0.644

RIPK2

0.577

IL1B

0.563

SUGT1

0.557

BRCC3

0.557

GSDMD

0.530

CARD8

0.525

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK9	G3TCK5_LOXAF	ENSLAFP00000011526	ENSLAFP00000011802	Uncharacterized protein.	Uncharacterized protein.	0.997
AK9	MAVS	ENSLAFP00000011526	ENSLAFP00000002595	Uncharacterized protein.	Mitochondrial antiviral signaling protein.	0.425
AK9	NLRC3	ENSLAFP00000011526	ENSLAFP00000006215	Uncharacterized protein.	NLR family CARD domain containing 3.	0.682
BRCC3	NLRC3	ENSLAFP00000011351	ENSLAFP00000006215	BRCA1/BRCA2-containing complex subunit 3.	NLR family CARD domain containing 3.	0.557
CARD8	GSDMD	ENSLAFP00000002966	ENSLAFP00000002281	Uncharacterized protein.	Gasdermin D.	0.745
CARD8	IL1B	ENSLAFP00000002966	ENSLAFP00000003388	Uncharacterized protein.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.517
CARD8	NLRC3	ENSLAFP00000002966	ENSLAFP00000006215	Uncharacterized protein.	NLR family CARD domain containing 3.	0.525
CARD8	PYCARD	ENSLAFP00000002966	ENSLAFP00000004815	Uncharacterized protein.	PYD and CARD domain containing.	0.684
CARD8	RIPK2	ENSLAFP00000002966	ENSLAFP00000022310	Uncharacterized protein.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.466
G3TCK5_LOXAF	AK9	ENSLAFP00000011802	ENSLAFP00000011526	Uncharacterized protein.	Uncharacterized protein.	0.997
G3TCK5_LOXAF	MAVS	ENSLAFP00000011802	ENSLAFP00000002595	Uncharacterized protein.	Mitochondrial antiviral signaling protein.	0.425
G3TCK5_LOXAF	NLRC3	ENSLAFP00000011802	ENSLAFP00000006215	Uncharacterized protein.	NLR family CARD domain containing 3.	0.682
GSDMD	CARD8	ENSLAFP00000002281	ENSLAFP00000002966	Gasdermin D.	Uncharacterized protein.	0.745
GSDMD	IL1B	ENSLAFP00000002281	ENSLAFP00000003388	Gasdermin D.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.809
GSDMD	NLRC3	ENSLAFP00000002281	ENSLAFP00000006215	Gasdermin D.	NLR family CARD domain containing 3.	0.530
GSDMD	PYCARD	ENSLAFP00000002281	ENSLAFP00000004815	Gasdermin D.	PYD and CARD domain containing.	0.811
IL1B	CARD8	ENSLAFP00000003388	ENSLAFP00000002966	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Uncharacterized protein.	0.517
IL1B	GSDMD	ENSLAFP00000003388	ENSLAFP00000002281	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Gasdermin D.	0.809
IL1B	NLRC3	ENSLAFP00000003388	ENSLAFP00000006215	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	NLR family CARD domain containing 3.	0.563
IL1B	PYCARD	ENSLAFP00000003388	ENSLAFP00000004815	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	PYD and CARD domain containing.	0.958

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