Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GFPT2Glutamine-fructose-6-phosphate transaminase 2. (682 aa)    
Predicted Functional Partners:
AMDHD2
N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.
    
 0.913
PPAT
Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.905
GPI
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.903
GLUL
Glutamine synthetase.
  
 
 0.894
CAD
Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.
   
 0.887
GNPNAT1
Glucosamine 6-phosphate N-acetyltransferase.
  
 0.887
HKDC1
Hexokinase domain containing 1.
   
 
 0.879
HK2
Hexokinase 2.
   
 
 0.879
GLS2
Glutaminase 2.
     
 0.865
MPI
Mannose-6-phosphate isomerase.
    
 0.835
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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