Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CNKSR2Connector enhancer of kinase suppressor of Ras 2. (1034 aa)    
Predicted Functional Partners:
KSR1
Kinase suppressor of ras 1.
    
 0.749
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.674
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.674
KSR2
Kinase suppressor of ras 2.
    
 0.669
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.645
LRRC7
Leucine rich repeat containing 7.
   
 
 0.605
MAP2K5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
    
 0.574
MAP2K1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
    
 0.574
MAP2K2
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.574
DLGAP3
DLG associated protein 3.
   
 
 0.572
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.