STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CNKSR2Connector enhancer of kinase suppressor of Ras 2. (1034 aa)    
Predicted Functional Partners:
KSR1
Kinase suppressor of ras 1.
    
 0.611
KSR2
Kinase suppressor of ras 2.
    
 0.534
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.525
IQGAP3
IQ motif containing GTPase activating protein 3.
     
 0.496
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.492
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.492
RALA
RAS like proto-oncogene A.
    
 0.470
RALB
RAS like proto-oncogene B.
    
 0.470
IL17RD
Interleukin 17 receptor D.
     
 0.448
MAP2K5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
    
 0.410
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.