STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CSKTyrosine-protein kinase. (450 aa)    
Predicted Functional Partners:
PAG1
Phosphoprotein membrane anchor with glycosphingolipid microdomains 1.
    
 0.956
EGFR
Receptor protein-tyrosine kinase.
    
 0.815
NTRK3
Tyrosine-protein kinase receptor.
    
  0.801
NTRK1
Tyrosine-protein kinase receptor.
    
  0.798
NTRK2
Tyrosine-protein kinase receptor.
    
  0.798
YES1
Tyrosine-protein kinase.
   
 0.760
SRC
Tyrosine-protein kinase.
   
 0.760
LPXN
Leupaxin.
   
 0.741
PXN
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
   
 0.741
PTPN22
Protein tyrosine phosphatase non-receptor type 22.
   
 0.737
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: medium (46%) [HD]