Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NDUFAF6NADH:ubiquinone oxidoreductase complex assembly factor 6. (333 aa)    
Predicted Functional Partners:
NDUFAF5
NADH:ubiquinone oxidoreductase complex assembly factor 5.
   
 0.967
ND1
NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
   
 
 0.912
TMEM186
Transmembrane protein 186.
   
 
 0.860
NDUFAF1
NADH:ubiquinone oxidoreductase complex assembly factor 1.
   
 
 0.837
KCNV2
Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family.
   
  
 0.799
NDUFAF4
NADH:ubiquinone oxidoreductase complex assembly factor 4.
     
 0.793
NDUFA9
Uncharacterized protein.
  
 
 0.791
RETSAT
Retinol saturase.
  
 
 0.773
PYROXD2
Pyridine nucleotide-disulphide oxidoreductase domain 2.
  
 
 0.773
NDUFAF7
Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
     
 0.771
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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