Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G3T012_LOXAFUncharacterized protein. (799 aa)    
Predicted Functional Partners:
PLK4
Polo like kinase 4.
   
 0.982
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.961
PLK1
Serine/threonine-protein kinase PLK.
   
 0.957
CEP85
Centrosomal protein 85.
    
 
 0.853
BORA
BORA aurora kinase A activator.
   
 
 0.848
NEDD1
NEDD1 gamma-tubulin ring complex targeting factor.
   
 0.829
CEP63
Centrosomal protein 63.
   
 
 0.800
SEH1L
SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family.
 
    
 0.783
CEP152
Centrosomal protein 152.
   
 0.771
G3TD28_LOXAF
Uncharacterized protein.
   
 
 0.762
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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