PRSS12 protein (Loxodonta africana) - STRING interaction network

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PRSS12

Serine protease 12; Belongs to the peptidase S1 family. (769 aa)

Predicted Functional Partners:

BOP1

0.578

MST1R

0.507

MET

0.507

G3TGW9_LOXAF

0.484

AGRN

0.469

SCN4B

0.457

CRBN

0.454

MUSK

0.428

MGAT5

0.416

CD109

0.405

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGRN	MUSK	ENSLAFP00000017347	ENSLAFP00000012848	Agrin.	Muscle associated receptor tyrosine kinase.	0.907
AGRN	PRSS12	ENSLAFP00000017347	ENSLAFP00000006279	Agrin.	Serine protease 12; Belongs to the peptidase S1 family.	0.469
BOP1	PRSS12	ENSLAFP00000000575	ENSLAFP00000006279	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Serine protease 12; Belongs to the peptidase S1 family.	0.578
CD109	PRSS12	ENSLAFP00000005681	ENSLAFP00000006279	CD109 molecule.	Serine protease 12; Belongs to the peptidase S1 family.	0.405
CRBN	PRSS12	ENSLAFP00000014780	ENSLAFP00000006279	Cereblon.	Serine protease 12; Belongs to the peptidase S1 family.	0.454
G3TGW9_LOXAF	PRSS12	ENSLAFP00000013755	ENSLAFP00000006279	Kazal-like domain-containing protein.	Serine protease 12; Belongs to the peptidase S1 family.	0.484
MET	MST1R	ENSLAFP00000009780	ENSLAFP00000005642	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Macrophage stimulating 1 receptor.	0.700
MET	PRSS12	ENSLAFP00000009780	ENSLAFP00000006279	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Serine protease 12; Belongs to the peptidase S1 family.	0.507
MGAT5	PRSS12	ENSLAFP00000013638	ENSLAFP00000006279	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase.	Serine protease 12; Belongs to the peptidase S1 family.	0.416
MGAT5	SCN4B	ENSLAFP00000013638	ENSLAFP00000007731	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase.	Sodium voltage-gated channel beta subunit 4.	0.433
MST1R	MET	ENSLAFP00000005642	ENSLAFP00000009780	Macrophage stimulating 1 receptor.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.700
MST1R	PRSS12	ENSLAFP00000005642	ENSLAFP00000006279	Macrophage stimulating 1 receptor.	Serine protease 12; Belongs to the peptidase S1 family.	0.507
MUSK	AGRN	ENSLAFP00000012848	ENSLAFP00000017347	Muscle associated receptor tyrosine kinase.	Agrin.	0.907
MUSK	PRSS12	ENSLAFP00000012848	ENSLAFP00000006279	Muscle associated receptor tyrosine kinase.	Serine protease 12; Belongs to the peptidase S1 family.	0.428
PRSS12	AGRN	ENSLAFP00000006279	ENSLAFP00000017347	Serine protease 12; Belongs to the peptidase S1 family.	Agrin.	0.469
PRSS12	BOP1	ENSLAFP00000006279	ENSLAFP00000000575	Serine protease 12; Belongs to the peptidase S1 family.	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.578
PRSS12	CD109	ENSLAFP00000006279	ENSLAFP00000005681	Serine protease 12; Belongs to the peptidase S1 family.	CD109 molecule.	0.405
PRSS12	CRBN	ENSLAFP00000006279	ENSLAFP00000014780	Serine protease 12; Belongs to the peptidase S1 family.	Cereblon.	0.454
PRSS12	G3TGW9_LOXAF	ENSLAFP00000006279	ENSLAFP00000013755	Serine protease 12; Belongs to the peptidase S1 family.	Kazal-like domain-containing protein.	0.484
PRSS12	MET	ENSLAFP00000006279	ENSLAFP00000009780	Serine protease 12; Belongs to the peptidase S1 family.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.507

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