Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SERPINB9Serpin family B member 9; Belongs to the serpin family. (377 aa)    
Predicted Functional Partners:
CTSG
Cathepsin G; Belongs to the peptidase S1 family.
   
 0.856
SERPINB10
Serpin family B member 10; Belongs to the serpin family.
     
  0.762
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.604
SERP2
Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family.
      
 0.558
SERPINB13
Serpin family B member 13; Belongs to the serpin family.
     
  0.552
G3U5T0_LOXAF
SERPIN domain-containing protein; Belongs to the serpin family.
     
  0.552
G3TBD7_LOXAF
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.549
G3UJ54_LOXAF
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.549
G3ULI4_LOXAF
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.456
SERPING1
Serpin family G member 1; Belongs to the serpin family.
  
0.454
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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