METTL16 protein (Loxodonta africana) - STRING interaction network

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METTL16

U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (597 aa)

Predicted Functional Partners:

METTL14

0.835

WTAP

0.794

MEPCE

0.768

ALKBH5

0.741

VIRMA

0.684

METTL5

0.671

BCDIN3D

0.668

ZCCHC4

0.654

METTL4

0.653

YTHDF1

0.653

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALKBH5	METTL14	ENSLAFP00000013004	ENSLAFP00000001552	AlkB homolog 5, RNA demethylase.	Methyltransferase like 14; Belongs to the MT-A70-like family.	0.858
ALKBH5	METTL16	ENSLAFP00000013004	ENSLAFP00000006301	AlkB homolog 5, RNA demethylase.	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]	0.741
ALKBH5	METTL4	ENSLAFP00000013004	ENSLAFP00000003758	AlkB homolog 5, RNA demethylase.	Methyltransferase like 4; Belongs to the MT-A70-like family.	0.559
ALKBH5	METTL5	ENSLAFP00000013004	ENSLAFP00000015124	AlkB homolog 5, RNA demethylase.	Methyltransferase like 5.	0.525
ALKBH5	VIRMA	ENSLAFP00000013004	ENSLAFP00000012840	AlkB homolog 5, RNA demethylase.	Vir like m6A methyltransferase associated.	0.673
ALKBH5	WTAP	ENSLAFP00000013004	ENSLAFP00000006163	AlkB homolog 5, RNA demethylase.	WT1 associated protein.	0.848
ALKBH5	YTHDF1	ENSLAFP00000013004	ENSLAFP00000020379	AlkB homolog 5, RNA demethylase.	YTH N6-methyladenosine RNA binding protein 1.	0.838
ALKBH5	ZCCHC4	ENSLAFP00000013004	ENSLAFP00000010225	AlkB homolog 5, RNA demethylase.	Zinc finger CCHC-type containing 4.	0.410
BCDIN3D	METTL16	ENSLAFP00000015407	ENSLAFP00000006301	BCDIN3 domain containing RNA methyltransferase.	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]	0.668
MEPCE	METTL16	ENSLAFP00000010324	ENSLAFP00000006301	Methylphosphate capping enzyme.	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]	0.768
METTL14	ALKBH5	ENSLAFP00000001552	ENSLAFP00000013004	Methyltransferase like 14; Belongs to the MT-A70-like family.	AlkB homolog 5, RNA demethylase.	0.858
METTL14	METTL16	ENSLAFP00000001552	ENSLAFP00000006301	Methyltransferase like 14; Belongs to the MT-A70-like family.	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]	0.835
METTL14	METTL4	ENSLAFP00000001552	ENSLAFP00000003758	Methyltransferase like 14; Belongs to the MT-A70-like family.	Methyltransferase like 4; Belongs to the MT-A70-like family.	0.915
METTL14	METTL5	ENSLAFP00000001552	ENSLAFP00000015124	Methyltransferase like 14; Belongs to the MT-A70-like family.	Methyltransferase like 5.	0.639
METTL14	VIRMA	ENSLAFP00000001552	ENSLAFP00000012840	Methyltransferase like 14; Belongs to the MT-A70-like family.	Vir like m6A methyltransferase associated.	0.935
METTL14	WTAP	ENSLAFP00000001552	ENSLAFP00000006163	Methyltransferase like 14; Belongs to the MT-A70-like family.	WT1 associated protein.	0.997
METTL14	YTHDF1	ENSLAFP00000001552	ENSLAFP00000020379	Methyltransferase like 14; Belongs to the MT-A70-like family.	YTH N6-methyladenosine RNA binding protein 1.	0.883
METTL14	ZCCHC4	ENSLAFP00000001552	ENSLAFP00000010225	Methyltransferase like 14; Belongs to the MT-A70-like family.	Zinc finger CCHC-type containing 4.	0.622
METTL16	ALKBH5	ENSLAFP00000006301	ENSLAFP00000013004	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]	AlkB homolog 5, RNA demethylase.	0.741
METTL16	BCDIN3D	ENSLAFP00000006301	ENSLAFP00000015407	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]	BCDIN3 domain containing RNA methyltransferase.	0.668

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