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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNJ14Potassium voltage-gated channel subfamily J member 14. (413 aa)    
Predicted Functional Partners:
KCNJ4
Potassium voltage-gated channel subfamily J member 4.
  
  
 
0.934
KCNJ2
Potassium voltage-gated channel subfamily J member 2.
  
  
 
0.927
KCNJ12
Uncharacterized protein.
  
  
 
0.927
KCNQ3
Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family.
   
 
 0.911
KCNQ4
Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family.
   
 
 0.911
KCNQ1
Ion_trans domain-containing protein; Belongs to the potassium channel family.
   
 
 0.911
GNAQ
G protein subunit alpha q.
   
 
  0.902
SCN4A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
    
 
 0.588
TMEM68
Transmembrane protein 68.
      
 0.517
NTN5
Netrin 5.
      
 0.504
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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