IRF1 protein (Loxodonta africana) - STRING interaction network

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IRF1

Interferon regulatory factor. (326 aa)

Predicted Functional Partners:

STAT1

0.987

MDM2

0.973

STUB1

0.936

EP300

0.889

CHD4

0.876

IRF8

0.850

STAT2

0.834

IRF2

0.830

STAT4

0.822

HDAC1

0.815

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHD4	EP300	ENSLAFP00000017802	ENSLAFP00000010281	Uncharacterized protein.	E1A binding protein p300.	0.769
CHD4	HDAC1	ENSLAFP00000017802	ENSLAFP00000004079	Uncharacterized protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.979
CHD4	IRF1	ENSLAFP00000017802	ENSLAFP00000006310	Uncharacterized protein.	Interferon regulatory factor.	0.876
EP300	CHD4	ENSLAFP00000010281	ENSLAFP00000017802	E1A binding protein p300.	Uncharacterized protein.	0.769
EP300	HDAC1	ENSLAFP00000010281	ENSLAFP00000004079	E1A binding protein p300.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.874
EP300	IRF1	ENSLAFP00000010281	ENSLAFP00000006310	E1A binding protein p300.	Interferon regulatory factor.	0.889
EP300	IRF8	ENSLAFP00000010281	ENSLAFP00000009178	E1A binding protein p300.	Interferon regulatory factor 8.	0.408
EP300	MDM2	ENSLAFP00000010281	ENSLAFP00000004935	E1A binding protein p300.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.965
EP300	STAT1	ENSLAFP00000010281	ENSLAFP00000020919	E1A binding protein p300.	Signal transducer and activator of transcription.	0.992
EP300	STAT2	ENSLAFP00000010281	ENSLAFP00000012473	E1A binding protein p300.	Signal transducer and activator of transcription.	0.975
EP300	STAT4	ENSLAFP00000010281	ENSLAFP00000010284	E1A binding protein p300.	Signal transducer and activator of transcription.	0.941
HDAC1	CHD4	ENSLAFP00000004079	ENSLAFP00000017802	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Uncharacterized protein.	0.979
HDAC1	EP300	ENSLAFP00000004079	ENSLAFP00000010281	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	E1A binding protein p300.	0.874
HDAC1	IRF1	ENSLAFP00000004079	ENSLAFP00000006310	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Interferon regulatory factor.	0.815
HDAC1	MDM2	ENSLAFP00000004079	ENSLAFP00000004935	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.739
HDAC1	STAT1	ENSLAFP00000004079	ENSLAFP00000020919	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Signal transducer and activator of transcription.	0.501
HDAC1	STAT2	ENSLAFP00000004079	ENSLAFP00000012473	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Signal transducer and activator of transcription.	0.494
HDAC1	STAT4	ENSLAFP00000004079	ENSLAFP00000010284	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Signal transducer and activator of transcription.	0.464
IRF1	CHD4	ENSLAFP00000006310	ENSLAFP00000017802	Interferon regulatory factor.	Uncharacterized protein.	0.876
IRF1	EP300	ENSLAFP00000006310	ENSLAFP00000010281	Interferon regulatory factor.	E1A binding protein p300.	0.889

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