Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GUCA2AGuanylate cyclase activator 2A. (114 aa)    
Predicted Functional Partners:
GUCY2C
Guanylate cyclase.
   
 0.994
GUCA2B
Guanylate cyclase activator 2B.
   
 
 0.993
TMIGD1
Transmembrane and immunoglobulin domain containing 1.
   
  
 0.926
CA2
Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family.
   
  
 0.796
EMD
Emerin.
      
 0.737
NPR3
Natriuretic peptide receptor 3.
   
 0.677
CNGA3
Cyclic nucleotide gated channel subunit alpha 3.
      
 0.598
OTOP3
Otopetrin 3.
      
 0.595
SLC51B
Solute carrier family 51 beta subunit.
   
  
 0.584
PRKG2
cGMP-dependent protein kinase.
      
 0.583
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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