STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1078 aa)    
Predicted Functional Partners:
DAXX
Death domain associated protein.
    
 0.993
UVSSA
UV stimulated scaffold protein A.
    
 0.991
USP11
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
 0.983
MDM2
E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.
    
 0.979
GMPS
Guanine monophosphate synthase.
   
 
 0.963
TRIM27
Tripartite motif containing 27.
    
 
 0.961
TRIP12
Thyroid hormone receptor interactor 12.
   
 
 0.961
FOXO4
Forkhead box O4.
   
 0.954
UHRF1
Ubiquitin like with PHD and ring finger domains 1.
    
 
 0.948
CHEK1
Checkpoint kinase 1; Belongs to the protein kinase superfamily.
    
 
 0.945
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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