Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
HTRA1HtrA serine peptidase 1. (483 aa)    
Predicted Functional Partners:
XIAP
X-linked inhibitor of apoptosis.
    
 0.942
PINK1
PTEN induced kinase 1.
    
 0.910
BIRC5
Baculoviral IAP repeat containing 5.
    
 0.837
ACAN
Aggrecan.
   
 
 0.836
MAPT
Microtubule-associated protein.
    
 
 0.787
GCM1
Glial cells missing transcription factor 1.
    
 
 0.738
BIRC2
Baculoviral IAP repeat containing 2.
    
 0.717
BIRC3
Baculoviral IAP repeat containing 3.
    
 0.717
BIRC7
Baculoviral IAP repeat containing 7.
    
 0.717
CYCS
Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
    
 0.709
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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