Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WDR87Uncharacterized protein. (1135 aa)    
Predicted Functional Partners:
G3ULN9_LOXAF
Uncharacterized protein.
 
      0.864
BFSP2
Beaded filament structural protein 2; Belongs to the intermediate filament family.
    
 0.535
RNLS
Renalase, FAD dependent amine oxidase.
      
 0.520
DNMBP
Dynamin binding protein.
      
 0.514
SIPA1L3
Signal induced proliferation associated 1 like 3.
     
 0.513
AKR1E2
Aldo-keto reductase family 1 member E2.
      
 0.498
G3TMK1_LOXAF
SH3 domain-containing protein.
  
 
  0.496
HTR3C
5-hydroxytryptamine receptor 3C; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
 
   0.492
LONP1
Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...]
      
 0.480
CRYBB3
Crystallin beta B3; Belongs to the beta/gamma-crystallin family.
    
 0.442
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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