Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEFF1Transmembrane protein with EGF like and two follistatin like domains 1. (366 aa)    
Predicted Functional Partners:
ZDHHC5
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
    
   0.676
MSANTD3
Myb/SANT DNA binding domain containing 3.
 
      0.667
ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6; Belongs to the glycosyltransferase 29 family.
      
 0.478
AACS
Acetoacetyl-CoA synthetase.
   
  
 0.420
CLDND1
Claudin domain containing 1.
    
   0.417
ZDHHC8
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
    
   0.413
WNT7A
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 
 0.400
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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