STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALADDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (331 aa)    
Predicted Functional Partners:
HMBS
Hydroxymethylbilane synthase.
 
 0.996
UROS
Uroporphyrinogen III synthase.
  
 0.982
ALAS2
5-aminolevulinate synthase.
    
 0.923
ALAS1
5-aminolevulinate synthase.
    
 0.892
UROD
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.867
CPOX
Uncharacterized protein.
  
 
 0.863
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
  
  
 0.821
PPOX
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
 
 0.813
OAT
Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.789
SPO11
SPO11 initiator of meiotic double stranded breaks.
     
  0.704
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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