Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OTPOrthopedia homeobox. (325 aa)    
Predicted Functional Partners:
ALX3
ALX homeobox 3.
   
  
 0.930
ARX
Aristaless related homeobox.
   
  
 0.888
DRGX
Dorsal root ganglia homeobox.
   
  
 0.886
ALX4
ALX homeobox 4.
   
    0.878
FEZF2
FEZ family zinc finger 2.
   
 0.532
TH
Tyrosine hydroxylase.
      
 0.529
ADSL
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.512
TRH
Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
      
 0.511
FOXG1
Uncharacterized protein.
   
 0.506
SIX6
SIX homeobox 6.
    
 
 0.497
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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