STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3T0I7_LOXAFVWFA domain-containing protein. (911 aa)    
Predicted Functional Partners:
CLCA2
Chloride channel accessory 2.
     
  0.754
LIX1
Limb and CNS expressed 1.
   
  
 0.610
FAM20B
FAM20B glycosaminoglycan xylosylkinase.
   
 
  0.547
UGT3A2
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 0.542
CWC25
CWC25 spliceosome associated protein homolog.
   
    0.539
C1orf109
Chromosome 1 open reading frame 109.
   
    0.533
SLCO1A2
Solute carrier organic anion transporter family member.
   
    0.530
MOCS3
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
   
  0.526
COCH
Cochlin.
    
 0.504
WFS1
Wolframin ER transmembrane glycoprotein.
    
 0.504
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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