STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRGPRFMAS related GPR family member F; Belongs to the G-protein coupled receptor 1 family. (343 aa)    
Predicted Functional Partners:
EFEMP2
EGF containing fibulin extracellular matrix protein 2.
   
 0.605
CNN1
Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
   
    0.588
PRRX2
Paired related homeobox 2.
    
 
 0.586
VGLL3
Vestigial like family member 3.
      
 0.582
FKBP10
Peptidylprolyl isomerase.
      
 0.582
ATOH8
Atonal bHLH transcription factor 8.
      
 0.578
TGFB1I1
Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
   
  
 0.553
ZDHHC13
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
      
 0.537
LTBP2
Latent transforming growth factor beta binding protein 2.
   
 0.529
PTGIS
Prostaglandin I2 synthase; Belongs to the cytochrome P450 family.
      
 0.517
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.