Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
P3H2Prolyl 3-hydroxylase 2. (703 aa)    
Predicted Functional Partners:
P3H4
Prolyl 3-hydroxylase family member 4 (non-enzymatic).
   
 0.820
COL12A1
Collagen type XII alpha 1 chain.
    
 0.781
PPIB
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.740
COL18A1
Collagen type XVIII alpha 1 chain.
   
 
 0.728
P4HA2
Prolyl 4-hydroxylase subunit alpha 2.
   
  
 0.657
PLOD3
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3.
   
 
 0.600
PPIC
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.572
G3TJV3_LOXAF
Uncharacterized protein.
      
 0.566
ADAMTSL4
ADAMTS like 4.
      
 0.563
SEMA3C
Semaphorin 3C; Belongs to the semaphorin family.
      
 0.558
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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