Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DRAM2DNA damage regulated autophagy modulator 2. (265 aa)    
Predicted Functional Partners:
SIPA1L1
Signal induced proliferation associated 1 like 1.
      
 0.599
THYN1
Thymocyte nuclear protein 1.
      
 0.577
TTC12
Tetratricopeptide repeat domain 12.
      
 0.505
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
      
 0.494
C8orf37
Chromosome 8 open reading frame 37.
      
 0.493
TP53INP2
Tumor protein p53 inducible nuclear protein 2.
      
 0.492
DHX40
DEAH-box helicase 40.
      
 0.489
PTER
Phosphotriesterase related.
      
 0.489
ISCA1
Iron-sulfur cluster assembly 1.
      
 0.486
LRAT
Lecithin retinol acyltransferase.
      
 0.480
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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