Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)    
Predicted Functional Partners:
MAPK14
Mitogen-activated protein kinase.
   
 0.874
MAPK10
Mitogen-activated protein kinase.
   
 0.864
MAPK8
Mitogen-activated protein kinase.
   
 0.864
MAPK9
Mitogen-activated protein kinase.
   
 0.860
MAPK13
Mitogen-activated protein kinase.
   
 0.828
MAPK12
Mitogen-activated protein kinase.
   
 0.828
MAPK1
Mitogen-activated protein kinase.
   
 0.726
MAPK3
Mitogen-activated protein kinase.
   
 0.726
MAPK7
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.557
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
   
 
 0.552
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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