STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDEM1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (627 aa)    
Predicted Functional Partners:
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
   
 
 0.944
EDEM3
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
    
 0.936
CANX
Calnexin.
   
 
 0.928
EDEM2
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
 
 0.882
XBP1
X-box binding protein 1.
   
 0.821
DNAJC10
DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.
    
 
 0.819
CLGN
Calmegin.
   
 
 0.800
SEL1L2
SEL1L2 adaptor subunit of ERAD E3 ligase.
   
 
 0.796
OS9
OS9 endoplasmic reticulum lectin.
    
 
 0.766
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
 
 0.745
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.