STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.989
APC
APC regulator of WNT signaling pathway.
    
 0.981
AXIN1
Axin 1.
   
 0.954
CCND1
Cyclin D1; Belongs to the cyclin family.
    
 0.953
DVL3
Dishevelled segment polarity protein 3.
   
 0.952
DVL2
Dishevelled segment polarity protein 2.
   
 0.952
AKT2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
0.951
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
0.951
MYC
Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
    
 0.950
CSNK1D
Casein kinase 1 delta.
    
 0.950
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.