Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3T0Q9_LOXAFGlutaredoxin domain-containing protein. (62 aa)    
Predicted Functional Partners:
BOLA1
BolA family member 1; Belongs to the BolA/IbaG family.
    
 
 0.968
ISCA2
Iron-sulfur cluster assembly 2.
   
 0.953
ISCA1
Iron-sulfur cluster assembly 1.
   
 0.827
ISCU
Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
   
 0.783
FXN
Frataxin.
   
 
 0.772
ABCB7
ATP binding cassette subfamily B member 7.
    
 
 0.756
LYRM4
Uncharacterized protein; Belongs to the complex I LYR family.
    
 0.747
SLC25A38
Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
      
 0.737
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
   
 
 0.718
NFS1
Aminotran_5 domain-containing protein.
    
 0.701
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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