close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NFAT5Nuclear factor of activated T cells 5. (1481 aa)    
Predicted Functional Partners:
CREB1
cAMP responsive element binding protein 1.
      
 0.710
GATA4
GATA binding protein 4.
   
 
 0.704
DKK2
Dickkopf WNT signaling pathway inhibitor 2.
      
 0.620
JUN
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
    
 
 0.602
STAT3
Signal transducer and activator of transcription.
      
 0.587
FOXP3
Forkhead box P3.
      
 0.581
REL
REL proto-oncogene, NF-kB subunit.
      
 0.535
CSRNP3
Cysteine and serine rich nuclear protein 3.
      
 0.516
GATA5
GATA binding protein 5.
   
 
 0.473
GATA3
GATA binding protein 3.
   
 
 0.464
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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