Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPTBSpectrin beta chain; Belongs to the spectrin family. (2329 aa)    
Predicted Functional Partners:
SPTA1
Spectrin alpha, erythrocytic 1.
   
0.943
SPTAN1
Spectrin alpha, non-erythrocytic 1.
   
 0.932
EPB41
Erythrocyte membrane protein band 4.1.
   
 0.855
ADD2
Adducin 2.
   
 
 0.842
DMTN
Dematin actin binding protein.
   
 
 0.823
EPB42
Erythrocyte membrane protein band 4.2.
   
 
 0.788
SLC4A1
Anion exchange protein.
   
 
 0.783
ANKRD60
ANK_REP_REGION domain-containing protein.
   
 0.640
ANK3
Ankyrin 3.
   
 0.640
ANK1
Ankyrin 1.
   
 0.640
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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