Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ARAP3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3. (1418 aa)    
Predicted Functional Partners:
RHOA
Ras homolog family member A.
   
 0.796
RHOB
Ras homolog family member B.
   
 0.789
RHOC
Uncharacterized protein.
   
 0.789
RAP1A
RAP1A, member of RAS oncogene family.
    
 0.777
G3T8N8_LOXAF
Uncharacterized protein.
    
 0.770
RAP1B
Uncharacterized protein.
    
 0.770
SH3KBP1
SH3 domain containing kinase binding protein 1.
    
 
 0.717
AGFG2
ArfGAP with FG repeats 2.
      
 0.677
ZBTB32
Zinc finger and BTB domain containing 32.
      
 0.657
YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.
    
 
 0.592
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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