Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TOXThymocyte selection associated high mobility group box. (526 aa)    
Predicted Functional Partners:
TOX3
TOX high mobility group box family member 3.
   
    0.926
TOX4
TOX high mobility group box family member 4.
   
    0.553
TIGIT
T cell immunoreceptor with Ig and ITIM domains.
   
  
 0.545
ACTR8
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.530
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 0.523
PENK
Proenkephalin.
  
   
 0.521
ACTR5
Actin related protein 5; Belongs to the actin family.
    
 0.520
INO80C
INO80 complex subunit C.
    
 0.519
TAF5
TATA-box binding protein associated factor 5.
   
 0.514
TAF5L
TATA-box binding protein associated factor 5 like.
   
 0.514
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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