STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HECW1E3 ubiquitin-protein ligase. (775 aa)    
Predicted Functional Partners:
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.708
DVL1
Dishevelled segment polarity protein 1.
    
 0.661
UBB
Ubiquitin B.
    
 0.660
UBC
Uncharacterized protein.
    
 0.660
PSMD4
Proteasome 26S subunit, non-ATPase 4.
    
 0.651
RPS27A
Ubiquitin-like domain-containing protein.
    
 0.626
G3U9C8_LOXAF
Ubiquitin-like domain-containing protein.
    
 0.626
SMAD6
Mothers against decapentaplegic homolog.
    
 0.623
SMAD7
Mothers against decapentaplegic homolog.
    
 0.623
SMAD4
Mothers against decapentaplegic homolog.
   
 0.622
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.