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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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filled nodes:
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TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (361 aa)    
Predicted Functional Partners:
KYNU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family.
  
 
 0.985
IDO1
Indoleamine 2,3-dioxygenase 1.
   
 
 0.965
AFMID
Arylformamidase.
  
 
 0.956
DDC
Dopa decarboxylase.
     
 0.940
TPH2
Tryptophan hydroxylase 2.
  
 
 0.913
IL4I1
Amine oxidase.
     
 0.895
TPH1
BH4_AAA_HYDROXYL_2 domain-containing protein.
  
 
 0.869
G3UBE5_LOXAF
Uncharacterized protein.
  
 
 0.869
G3TRE3_LOXAF
Amine oxidase.
     
  0.821
G3UN85_LOXAF
Amine oxidase.
     
  0.821
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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