Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAGI3Membrane associated guanylate kinase, WW and PDZ domain containing 3. (1392 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
   
 0.948
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 0.900
MAGI1
Membrane associated guanylate kinase, WW and PDZ domain containing 1.
   
 0.884
MAGI2
Membrane associated guanylate kinase, WW and PDZ domain containing 2.
   
 0.883
RAPGEF6
Uncharacterized protein.
    
 0.867
AK9
Uncharacterized protein.
   
 0.859
G3TCK5_LOXAF
Uncharacterized protein.
   
 0.859
JUP
Junction plakoglobin.
   
 0.856
UCK1
Uridine-cytidine kinase 1.
   
 0.854
UCK2
Uridine-cytidine kinase 2.
   
 0.854
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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