STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDONCell adhesion associated, oncogene regulated. (1238 aa)    
Predicted Functional Partners:
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.975
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.955
SHH
Sonic hedgehog signaling molecule.
    
 0.955
PTCH1
Patched 1.
    
 0.954
BOC
BOC cell adhesion associated, oncogene regulated.
   
 0.944
PTCH2
Patched 2.
    
 0.939
SMO
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
   
 0.926
LRP2
LDL receptor related protein 2.
     
 0.882
CDH4
Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.689
CDH2
Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.689
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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