STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDONCell adhesion associated, oncogene regulated. (1238 aa)    
Predicted Functional Partners:
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.991
SHH
Sonic hedgehog signaling molecule.
    
 0.985
BOC
BOC cell adhesion associated, oncogene regulated.
    
0.967
PTCH2
Patched 2.
    
 0.965
LRP2
LDL receptor related protein 2.
     
 0.906
PTCH1
Patched 1.
    
 0.894
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.859
SMO
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
   
 0.601
CDH15
Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.512
SPAG9
Sperm associated antigen 9.
     
 0.482
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.