Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GUCA1AUncharacterized protein. (202 aa)    
Predicted Functional Partners:
GUCY2D
Guanylate cyclase.
   
 0.915
GUCA1B
Guanylate cyclase activator 1B.
   
 
  0.887
GUCY2F
Guanylate cyclase.
   
 0.865
G3U1X3_LOXAF
Guanylate cyclase.
   
 0.865
CNGA1
Cyclic nucleotide gated channel subunit alpha 1.
   
 0.758
GUF1
Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
      
 0.702
LENEP
Lens epithelial protein.
      
 0.682
VOPP1
VOPP1 WW domain binding protein.
      
 0.669
NPR1
Guanylate cyclase.
   
 0.627
PRPH2
Peripherin 2.
   
  
 0.606
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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