STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WDR44WD repeat domain 44. (912 aa)    
Predicted Functional Partners:
VAPB
VAMP associated protein B and C.
   
 
 0.814
VAPA
VAMP associated protein A.
   
 
 0.696
RABGEF1
Uncharacterized protein.
   
  
 0.629
OSBPL9
Oxysterol-binding protein; Belongs to the OSBP family.
    
 
 0.626
YIPF6
Protein YIPF.
   
  
 0.594
LSM7
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated.
    
   0.589
AQR
RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
      
 0.576
RAB3GAP1
RAB3 GTPase activating protein catalytic subunit 1.
   
  
 0.566
RAB3GAP2
RAB3 GTPase activating non-catalytic protein subunit 2.
   
  
 0.562
GALNT12
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.546
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.