Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTPN14Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1186 aa)    
Predicted Functional Partners:
WWC1
WW and C2 domain containing 1.
   
 0.957
LATS1
Large tumor suppressor kinase 1.
    
 
 0.882
KLHL6
BTB domain-containing protein.
      
 0.829
WWP2
E3 ubiquitin-protein ligase.
   
 
 0.795
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.
    
 0.756
WWC3
WWC family member 3.
    
 0.751
YAP1
Yes associated protein 1.
   
 
 0.734
WWTR1
WW domain containing transcription regulator 1.
   
 
 0.734
PTPRE
Receptor-type tyrosine-protein phosphatase.
    
 
 0.734
MAGI1
Membrane associated guanylate kinase, WW and PDZ domain containing 1.
    
 
 0.711
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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