STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKCSHProtein kinase C substrate 80K-H. (534 aa)    
Predicted Functional Partners:
GANAB
Glucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family.
   
 0.997
SEC63
SEC63 homolog, protein translocation regulator.
      
 0.725
SI
Sucrase-isomaltase.
   
 0.664
MYORG
Myogenesis regulating glycosidase (putative); Belongs to the glycosyl hydrolase 31 family.
   
 0.664
MGAM
Maltase-glucoamylase.
   
 0.664
GAA
Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family.
   
 0.664
C9orf24
Chromosome 9 open reading frame 24.
   
 0.664
DDOST
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]
   
 
 0.634
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.545
PKD2
Polycystin 2, transient receptor potential cation channel.
      
 0.526
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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