Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRKCSHProtein kinase C substrate 80K-H. (534 aa)    
Predicted Functional Partners:
GANAB
Glucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family.
   
 0.999
GNPTAB
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta.
    
 0.945
CANX
Calnexin.
   
 0.917
SEC63
SEC63 homolog, protein translocation regulator.
   
  
 0.806
CALR
Calreticulin.
   
 0.793
G3THW4_LOXAF
Calreticulin.
   
 0.793
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.778
P4HB
Protein disulfide-isomerase.
   
 0.745
MYDGF
Myeloid derived growth factor.
   
   0.712
ALG5
ALG5 dolichyl-phosphate beta-glucosyltransferase.
   
  
 0.699
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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