RNGTT protein (Loxodonta africana) - STRING interaction network

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RNGTT

Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (597 aa)

Predicted Functional Partners:

RNMT

0.984

SUPT5H

0.979

POLR2A

0.927

POLR2C

0.922

POLR2D

0.900

POLR2G

0.897

POLR2I

0.892

CMTR1

0.829

POLR2E

0.823

POLR2J

0.822

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMTR1	RNGTT	ENSLAFP00000014498	ENSLAFP00000006821	Cap methyltransferase 1.	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.	0.829
CMTR1	RNMT	ENSLAFP00000014498	ENSLAFP00000020854	Cap methyltransferase 1.	mRNA cap guanine-N7 methyltransferase.	0.416
POLR2A	POLR2C	ENSLAFP00000019477	ENSLAFP00000028614	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II subunit C.	0.998
POLR2A	POLR2D	ENSLAFP00000019477	ENSLAFP00000001545	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II subunit D.	0.998
POLR2A	POLR2E	ENSLAFP00000019477	ENSLAFP00000024181	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II subunit E.	0.998
POLR2A	POLR2G	ENSLAFP00000019477	ENSLAFP00000003629	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II subunit G.	0.998
POLR2A	POLR2I	ENSLAFP00000019477	ENSLAFP00000013012	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.998
POLR2A	POLR2J	ENSLAFP00000019477	ENSLAFP00000016360	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II subunit J.	0.997
POLR2A	RNGTT	ENSLAFP00000019477	ENSLAFP00000006821	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.	0.927
POLR2A	RNMT	ENSLAFP00000019477	ENSLAFP00000020854	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	mRNA cap guanine-N7 methyltransferase.	0.836
POLR2A	SUPT5H	ENSLAFP00000019477	ENSLAFP00000025318	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Transcription elongation factor SPT5.	0.988
POLR2C	POLR2A	ENSLAFP00000028614	ENSLAFP00000019477	RNA polymerase II subunit C.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.998
POLR2C	POLR2D	ENSLAFP00000028614	ENSLAFP00000001545	RNA polymerase II subunit C.	RNA polymerase II subunit D.	0.999
POLR2C	POLR2E	ENSLAFP00000028614	ENSLAFP00000024181	RNA polymerase II subunit C.	RNA polymerase II subunit E.	0.999
POLR2C	POLR2G	ENSLAFP00000028614	ENSLAFP00000003629	RNA polymerase II subunit C.	RNA polymerase II subunit G.	0.999
POLR2C	POLR2I	ENSLAFP00000028614	ENSLAFP00000013012	RNA polymerase II subunit C.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.998
POLR2C	POLR2J	ENSLAFP00000028614	ENSLAFP00000016360	RNA polymerase II subunit C.	RNA polymerase II subunit J.	0.994
POLR2C	RNGTT	ENSLAFP00000028614	ENSLAFP00000006821	RNA polymerase II subunit C.	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.	0.922
POLR2C	RNMT	ENSLAFP00000028614	ENSLAFP00000020854	RNA polymerase II subunit C.	mRNA cap guanine-N7 methyltransferase.	0.713
POLR2C	SUPT5H	ENSLAFP00000028614	ENSLAFP00000025318	RNA polymerase II subunit C.	Transcription elongation factor SPT5.	0.962

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