Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATM | MRE11 | ENSLAFP00000006871 | ENSLAFP00000019954 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.998 |
| ATM | NSD2 | ENSLAFP00000006871 | ENSLAFP00000006847 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Nuclear receptor binding SET domain protein 2. | 0.590 |
| ATM | RAD50 | ENSLAFP00000006871 | ENSLAFP00000008189 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Zinc-hook domain-containing protein. | 0.997 |
| ATM | TP53BP1 | ENSLAFP00000006871 | ENSLAFP00000001013 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Tumor protein p53 binding protein 1. | 0.985 |
| CAMKMT | NSD2 | ENSLAFP00000015172 | ENSLAFP00000006847 | Calmodulin-lysine N-methyltransferase. | Nuclear receptor binding SET domain protein 2. | 0.680 |
| CAMKMT | PLOD2 | ENSLAFP00000015172 | ENSLAFP00000001614 | Calmodulin-lysine N-methyltransferase. | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. | 0.900 |
| CAMKMT | PLOD3 | ENSLAFP00000015172 | ENSLAFP00000023656 | Calmodulin-lysine N-methyltransferase. | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. | 0.900 |
| EED | NSD2 | ENSLAFP00000021138 | ENSLAFP00000006847 | Embryonic ectoderm development. | Nuclear receptor binding SET domain protein 2. | 0.633 |
| G3UG48_LOXAF | NSD2 | ENSLAFP00000026806 | ENSLAFP00000006847 | Uncharacterized protein. | Nuclear receptor binding SET domain protein 2. | 0.681 |
| MRE11 | ATM | ENSLAFP00000019954 | ENSLAFP00000006871 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.998 |
| MRE11 | NSD2 | ENSLAFP00000019954 | ENSLAFP00000006847 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Nuclear receptor binding SET domain protein 2. | 0.662 |
| MRE11 | RAD50 | ENSLAFP00000019954 | ENSLAFP00000008189 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Zinc-hook domain-containing protein. | 0.999 |
| MRE11 | TP53BP1 | ENSLAFP00000019954 | ENSLAFP00000001013 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Tumor protein p53 binding protein 1. | 0.846 |
| NKX2-5 | NSD2 | ENSLAFP00000023214 | ENSLAFP00000006847 | NK2 homeobox 5. | Nuclear receptor binding SET domain protein 2. | 0.609 |
| NSD2 | ATM | ENSLAFP00000006847 | ENSLAFP00000006871 | Nuclear receptor binding SET domain protein 2. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.590 |
| NSD2 | CAMKMT | ENSLAFP00000006847 | ENSLAFP00000015172 | Nuclear receptor binding SET domain protein 2. | Calmodulin-lysine N-methyltransferase. | 0.680 |
| NSD2 | EED | ENSLAFP00000006847 | ENSLAFP00000021138 | Nuclear receptor binding SET domain protein 2. | Embryonic ectoderm development. | 0.633 |
| NSD2 | G3UG48_LOXAF | ENSLAFP00000006847 | ENSLAFP00000026806 | Nuclear receptor binding SET domain protein 2. | Uncharacterized protein. | 0.681 |
| NSD2 | MRE11 | ENSLAFP00000006847 | ENSLAFP00000019954 | Nuclear receptor binding SET domain protein 2. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.662 |
| NSD2 | NKX2-5 | ENSLAFP00000006847 | ENSLAFP00000023214 | Nuclear receptor binding SET domain protein 2. | NK2 homeobox 5. | 0.609 |
page 1 of 2