STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLL2Metalloendopeptidase. (1022 aa)    
Predicted Functional Partners:
CHRD
Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
   
 
 0.773
PCOLCE
Procollagen C-endopeptidase enhancer.
   
 0.751
PCOLCE2
Procollagen C-endopeptidase enhancer 2.
   
 0.564
COL3A1
Collagen type III alpha 1 chain.
   
 0.470
GDF11
Growth differentiation factor 11.
    
 
 0.458
GRIN2B
Glutamate ionotropic receptor NMDA type subunit 2B.
     
  0.443
COL5A2
Collagen type V alpha 2 chain.
   
 0.431
MSTN
Myostatin.
    
 
 0.429
LOXL3
Lysyl oxidase like 3.
   
 0.420
LOXL4
Lysyl oxidase like 4.
   
 0.418
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.