STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EHMT2Euchromatic histone lysine methyltransferase 2. (1225 aa)    
Predicted Functional Partners:
G3UFS4_LOXAF
Uncharacterized protein.
 
 
 0.996
EHMT1
Euchromatic histone lysine methyltransferase 1.
   
 0.969
PLOD3
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3.
    
  0.964
G3SUK2_LOXAF
Uncharacterized protein.
   
 0.956
CDYL
Chromodomain Y like.
   
 0.945
KDM1A
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
   
 0.916
CAMKMT
Calmodulin-lysine N-methyltransferase.
     
 0.909
PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2.
    
  0.904
CBX5
Chromobox 5.
    
 0.898
PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1.
    
 0.897
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.