Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IKZF2IKAROS family zinc finger 2. (526 aa)    
Predicted Functional Partners:
IKZF1
IKAROS family zinc finger 1.
   
 
 0.811
G3U948_LOXAF
Uncharacterized protein.
   
 
 0.811
IKZF5
IKAROS family zinc finger 5.
    
 
 0.788
IKZF3
IKAROS family zinc finger 3.
   
   0.754
FOXP3
Forkhead box P3.
    
 0.721
SLC26A5
Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
   
 0.583
TRERF1
Transcriptional regulating factor 1.
    
 
 0.549
MAP3K8
Mitogen-activated protein kinase kinase kinase 8.
    
 
 0.546
POU2AF1
POU class 2 homeobox associating factor 1.
   
  
 0.529
CRBN
Cereblon.
    
 
 0.523
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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