Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CD69CD69 molecule. (199 aa)    
Predicted Functional Partners:
CD4
CD4 molecule.
   
 0.829
KLRF1
Killer cell lectin like receptor F1.
   
 0.781
S1PR4
Sphingosine-1-phosphate receptor 4; Belongs to the G-protein coupled receptor 1 family.
    
 0.779
CCR7
C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.741
CLECL1
C-type lectin domain-containing protein.
   
 0.728
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
   
  
 0.725
FOXP3
Forkhead box P3.
      
 0.718
G3U4G1_LOXAF
Ig-like domain-containing protein.
   
 0.693
CD27
CD27 molecule.
   
  
 0.681
CD44
CD44 molecule (Indian blood group).
    
 0.669
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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