Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDC20BCell division cycle 20B. (486 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
   
 0.995
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.991
PTTG1
Uncharacterized protein.
   
 0.991
BUB1B
Uncharacterized protein.
   
 0.991
CDC27
Cell division cycle 27.
   
 0.986
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.982
CDC16
Cell division cycle 16.
   
 0.978
ANAPC2
Anaphase promoting complex subunit 2; Belongs to the cullin family.
   
 0.978
CDC23
Cell division cycle 23.
   
 0.978
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
 0.978
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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