Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CA5ACarbonic anhydrase 5A; Belongs to the alpha-carbonic anhydrase family. (257 aa)    
Predicted Functional Partners:
TMEM59
Transmembrane protein 59.
   
  
 0.539
RPF2
Ribosome production factor 2 homolog.
   
 
 0.529
DGKD
Diacylglycerol kinase.
   
  
 0.488
NOC2L
Uncharacterized protein.
   
  
 0.466
GRWD1
Glutamate rich WD repeat containing 1.
   
  
 0.454
WDR43
WD repeat domain 43.
   
    0.441
GTPBP4
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
  
 0.431
RRP12
Ribosomal RNA processing 12 homolog.
   
  
 0.428
PWP2
WD_REPEATS_REGION domain-containing protein.
   
    0.421
RRS1
Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.
   
 
 0.421
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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